This guide contains information about places where you can stop for the night when driving from Saint Louis, Missouri to Myrtle Beach, South Carolina. Total distance for the trip is around 895 miles with a driving time of approximately 13 hours 19 mins. Cities and towns with hotels that are on the fastest route between Saint Louis and Myrtle Beach are listed below. (Driving times are approximate and will vary with traffic and weather conditions.)

174 miles from Saint Louis (2 hours 41 mins)
723 miles from Myrtle Beach (10 hours 52 mins)
308 miles from Saint Louis (4 hours 31 mins)
590 miles from Myrtle Beach (8 hours 57 mins)
485 miles from Saint Louis (7 hours 2 mins)
411 miles from Myrtle Beach (6 hours 22 mins)
599 miles from Saint Louis (8 hours 49 mins)
305 miles from Myrtle Beach (4 hours 43 mins)
659 miles from Saint Louis (9 hours 43 mins)
241 miles from Myrtle Beach (3 hours 50 mins)
747 miles from Saint Louis (10 hours 56 mins)
153 miles from Myrtle Beach (2 hours 33 mins)
826 miles from Saint Louis (12 hours 4 mins)
67.3 miles from Myrtle Beach (1 hour 19 mins)

Popular Hotels In Myrtle Beach

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Please make sure you read your reservation's cancellation policy!
You'll be given this information with the available room rates after you select a hotel and specify dates. Many hotels have cancellation penalties associated with their best rates. Most offer "Book Now and Pay Later" options that are less restrictive, but slightly more expensive.